The Gunsaulus Mystery is a 1921 American silent race film directed, produced, and written by Oscar Micheaux. The film was inspired by events and figures in the 1913-1915 trial of Leo Frank, a Jewish man, for the murder of Mary Phagan, a Christian girl. The film is now believed to be lost.

• Micheaux Picture Corporation
• Evelyn Preer
• Edward R. Abrams
• Lawrence Chenault
• Louis De Bulger
• E.G. Tatum