Miss Tacuarembó is a unique mixture of drama, comedy, musical with touches of parody and nostalgia which for its beautiful narration will attract many open-minded viewers not only in Latin American world. The story of Natalia, the main hero, and her life's struggles is shown in different three eras of her life.

• Natalia Oreiro
• Mirella Pascual
• Mike Amigorena
• Diego Reinhold
• Rossy de Palma
• Alejandro Tous
• Mónica Villa
• Graciela Borges